Pronounce Despair as D EH S P AH IY R.
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loss of hope; utter hopelessness
despair, desperation(noun)a state in which all hope is lost or absent
"in the depths of despair"; "they were rescued from despair at the last minute"; "courage born of desperation"
despair(verb)the feeling that everything is wrong and nothing will turn out well
"they moaned in despair and dismay"; "one harsh word would send her into the depths of despair"
despair(verb)abandon hope; give up hope; lose heart
"Don't despair--help is on the way!"
utter loss of hopethe endless drought drove the farmers to despair
the state of being discouragedthe other team's temporary lead caused some momentary despair
to lose all hope or confidencewe despaired when we saw how little time we had left to complete our project
Despair drove him to attempt suicide.