Pronounce Irrespective as IY R R EH S P EH K T IY V EH.
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without regard for conditions, circumstances, or consequences; regardless of
regardless, irrespective, disregardless, no matter, disregarding(adverb)in spite of everything; without regard to drawbacks
"he carried on regardless of the difficulties"
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We are apt to watch television, irrespective of what program is on.
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